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xyz micropositioner x-lrm  (Zaber Technologies)

 
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    Zaber Technologies xyz micropositioner x-lrm
    Design and experimental setup of the MMP system. (a) Schematic of the MMP design showing an isometric, see-through view. The MMP includes two injection channels (Injection 1 and Injection 2) and an aspiration channel, with mixing channels located below the holder key. The base of the MMP features a central mesa where fluidic interactions occur. The inset shows a top-down view of the mesa with injection and aspiration regions. (b) Diagram of the experimental setup, including the <t>XYZ</t> <t>micropositioner,</t> syringe pump, and MMP. Syringe pump channels are labeled for aspiration, Injection 1 (molecule, 100%), and Injection 2 (buffer, 0%). These injections create distinct concentration-varying flow dipoles of biochemical concentrations that are confined under the MMP mesa due to aspiration and the surrounding immersion fluid. Inset: The concentration gradient HFC profiles (100%, 50%, 0%) generated on adherent cells within the Petri dish. (c) Simulation of concentration gradient profiles formed by the mixing of the molecule (100%) and buffer (0%) within the MMP channels. The left panel shows the mixing process creating a 50% concentration in the middle channel, while the right panel shows the full setup with the aspiration and injection mechanisms confining the flow. (d) The micrograph shows the experimental setup, consisting of inverted fluorescence microscope, syringe pump equipped with microfluidic syringes, 3D-printed XYZ micropositioner, and 3D-printed MMP. The micrograph in the inset shows Injection 1, Injection 2, and aspiration directions through the MMP.
    Xyz Micropositioner X Lrm, supplied by Zaber Technologies, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/x-lrm/xyz+micropositioner+x+lrm/pmc11742695-40-14-18
    Average 90 stars, based on 1 article reviews
    xyz micropositioner x-lrm - by Bioz Stars, 2026-09
    90/100 stars

    Images

    1) Product Images from "Microfluidic mixing probe: generating multiple concentration-varying flow dipoles"

    Article Title: Microfluidic mixing probe: generating multiple concentration-varying flow dipoles

    Journal: Scientific Reports

    doi: 10.1038/s41598-025-85797-3

    Design and experimental setup of the MMP system. (a) Schematic of the MMP design showing an isometric, see-through view. The MMP includes two injection channels (Injection 1 and Injection 2) and an aspiration channel, with mixing channels located below the holder key. The base of the MMP features a central mesa where fluidic interactions occur. The inset shows a top-down view of the mesa with injection and aspiration regions. (b) Diagram of the experimental setup, including the XYZ micropositioner, syringe pump, and MMP. Syringe pump channels are labeled for aspiration, Injection 1 (molecule, 100%), and Injection 2 (buffer, 0%). These injections create distinct concentration-varying flow dipoles of biochemical concentrations that are confined under the MMP mesa due to aspiration and the surrounding immersion fluid. Inset: The concentration gradient HFC profiles (100%, 50%, 0%) generated on adherent cells within the Petri dish. (c) Simulation of concentration gradient profiles formed by the mixing of the molecule (100%) and buffer (0%) within the MMP channels. The left panel shows the mixing process creating a 50% concentration in the middle channel, while the right panel shows the full setup with the aspiration and injection mechanisms confining the flow. (d) The micrograph shows the experimental setup, consisting of inverted fluorescence microscope, syringe pump equipped with microfluidic syringes, 3D-printed XYZ micropositioner, and 3D-printed MMP. The micrograph in the inset shows Injection 1, Injection 2, and aspiration directions through the MMP.
    Figure Legend Snippet: Design and experimental setup of the MMP system. (a) Schematic of the MMP design showing an isometric, see-through view. The MMP includes two injection channels (Injection 1 and Injection 2) and an aspiration channel, with mixing channels located below the holder key. The base of the MMP features a central mesa where fluidic interactions occur. The inset shows a top-down view of the mesa with injection and aspiration regions. (b) Diagram of the experimental setup, including the XYZ micropositioner, syringe pump, and MMP. Syringe pump channels are labeled for aspiration, Injection 1 (molecule, 100%), and Injection 2 (buffer, 0%). These injections create distinct concentration-varying flow dipoles of biochemical concentrations that are confined under the MMP mesa due to aspiration and the surrounding immersion fluid. Inset: The concentration gradient HFC profiles (100%, 50%, 0%) generated on adherent cells within the Petri dish. (c) Simulation of concentration gradient profiles formed by the mixing of the molecule (100%) and buffer (0%) within the MMP channels. The left panel shows the mixing process creating a 50% concentration in the middle channel, while the right panel shows the full setup with the aspiration and injection mechanisms confining the flow. (d) The micrograph shows the experimental setup, consisting of inverted fluorescence microscope, syringe pump equipped with microfluidic syringes, 3D-printed XYZ micropositioner, and 3D-printed MMP. The micrograph in the inset shows Injection 1, Injection 2, and aspiration directions through the MMP.

    Techniques Used: Injection, Labeling, Concentration Assay, Generated, Fluorescence, Microscopy

    Related Articles

    other:

    Article Title: 3D Printed Microfluidic Probes
    Article Snippet: Upon aligning the MFP with the objective of the microscope, the Z stage (X-LRM, Zaber, Vancouver, Canada) is used to slowly approach the substrate.



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    Design and experimental setup of the MMP system. (a) Schematic of the MMP design showing an isometric, see-through view. The MMP includes two injection channels (Injection 1 and Injection 2) and an aspiration channel, with mixing channels located below the holder key. The base of the MMP features a central mesa where fluidic interactions occur. The inset shows a top-down view of the mesa with injection and aspiration regions. (b) Diagram of the experimental setup, including the <t>XYZ</t> <t>micropositioner,</t> syringe pump, and MMP. Syringe pump channels are labeled for aspiration, Injection 1 (molecule, 100%), and Injection 2 (buffer, 0%). These injections create distinct concentration-varying flow dipoles of biochemical concentrations that are confined under the MMP mesa due to aspiration and the surrounding immersion fluid. Inset: The concentration gradient HFC profiles (100%, 50%, 0%) generated on adherent cells within the Petri dish. (c) Simulation of concentration gradient profiles formed by the mixing of the molecule (100%) and buffer (0%) within the MMP channels. The left panel shows the mixing process creating a 50% concentration in the middle channel, while the right panel shows the full setup with the aspiration and injection mechanisms confining the flow. (d) The micrograph shows the experimental setup, consisting of inverted fluorescence microscope, syringe pump equipped with microfluidic syringes, 3D-printed XYZ micropositioner, and 3D-printed MMP. The micrograph in the inset shows Injection 1, Injection 2, and aspiration directions through the MMP.
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    Design and experimental setup of the MMP system. (a) Schematic of the MMP design showing an isometric, see-through view. The MMP includes two injection channels (Injection 1 and Injection 2) and an aspiration channel, with mixing channels located below the holder key. The base of the MMP features a central mesa where fluidic interactions occur. The inset shows a top-down view of the mesa with injection and aspiration regions. (b) Diagram of the experimental setup, including the XYZ micropositioner, syringe pump, and MMP. Syringe pump channels are labeled for aspiration, Injection 1 (molecule, 100%), and Injection 2 (buffer, 0%). These injections create distinct concentration-varying flow dipoles of biochemical concentrations that are confined under the MMP mesa due to aspiration and the surrounding immersion fluid. Inset: The concentration gradient HFC profiles (100%, 50%, 0%) generated on adherent cells within the Petri dish. (c) Simulation of concentration gradient profiles formed by the mixing of the molecule (100%) and buffer (0%) within the MMP channels. The left panel shows the mixing process creating a 50% concentration in the middle channel, while the right panel shows the full setup with the aspiration and injection mechanisms confining the flow. (d) The micrograph shows the experimental setup, consisting of inverted fluorescence microscope, syringe pump equipped with microfluidic syringes, 3D-printed XYZ micropositioner, and 3D-printed MMP. The micrograph in the inset shows Injection 1, Injection 2, and aspiration directions through the MMP.

    Journal: Scientific Reports

    Article Title: Microfluidic mixing probe: generating multiple concentration-varying flow dipoles

    doi: 10.1038/s41598-025-85797-3

    Figure Lengend Snippet: Design and experimental setup of the MMP system. (a) Schematic of the MMP design showing an isometric, see-through view. The MMP includes two injection channels (Injection 1 and Injection 2) and an aspiration channel, with mixing channels located below the holder key. The base of the MMP features a central mesa where fluidic interactions occur. The inset shows a top-down view of the mesa with injection and aspiration regions. (b) Diagram of the experimental setup, including the XYZ micropositioner, syringe pump, and MMP. Syringe pump channels are labeled for aspiration, Injection 1 (molecule, 100%), and Injection 2 (buffer, 0%). These injections create distinct concentration-varying flow dipoles of biochemical concentrations that are confined under the MMP mesa due to aspiration and the surrounding immersion fluid. Inset: The concentration gradient HFC profiles (100%, 50%, 0%) generated on adherent cells within the Petri dish. (c) Simulation of concentration gradient profiles formed by the mixing of the molecule (100%) and buffer (0%) within the MMP channels. The left panel shows the mixing process creating a 50% concentration in the middle channel, while the right panel shows the full setup with the aspiration and injection mechanisms confining the flow. (d) The micrograph shows the experimental setup, consisting of inverted fluorescence microscope, syringe pump equipped with microfluidic syringes, 3D-printed XYZ micropositioner, and 3D-printed MMP. The micrograph in the inset shows Injection 1, Injection 2, and aspiration directions through the MMP.

    Article Snippet: The MMP also incorporates a custom-designed, 3D-printed twist-lock assembly that secures it to a computer-controlled XYZ micropositioner (X-LRM, Zaber Technologies) for precise positional control during operation, and includes ports for tubing connectors, which are shrink-fitted to ensure airtight connections (Fig. b).

    Techniques: Injection, Labeling, Concentration Assay, Generated, Fluorescence, Microscopy